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	<title>IMVA - International Medical Veritas Association &#187; Multiple Sclerosis</title>
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		<title>Multiple Sclerosis</title>
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		<pubDate>Wed, 10 Mar 2010 17:04:24 +0000</pubDate>
		<dc:creator>Mark Sircus - Director</dc:creator>
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		<description><![CDATA[Magnesium, Selenium, Iodine and Mercury Connection

 There is no disputing the fact that  modern pharmaceutical medicine has not solved nor cured any of the modern  chronic disease plagues that are morphing out of control into pandemics. What  is going on in the areas of cancer, diabetes, heart disease, strokes and  neurological disease is painting a horrific image of the failure of  contemporary medicine, which seems unable to learn anything about what will  make a difference for their patients. They are good to go with words of promise  but they don’t deliver and things ...

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<p class="subtittleBordo"><strong>Magnesium, Selenium, Iodine and Mercury Connection</strong></p>
<p class="alinharCentralizar"><img src="http://imva.info/wp-content/uploads/2010/03/clip_image0022.jpg" alt="Image" width="336" height="224" /></p>
<p><span class="paragrafo"> </span>There is no disputing the fact that  modern pharmaceutical medicine has not solved nor cured any of the modern  chronic disease plagues that are morphing out of control into pandemics. What  is going on in the areas of cancer, diabetes, heart disease, strokes and  neurological disease is painting a horrific image of the failure of  contemporary medicine, which seems unable to learn anything about what will  make a difference for their patients. They are good to go with words of promise  but they don’t deliver and things are only getting worse in terms of public  health.</p>
<p><span class="paragrafo"> </span>It is difficult to treat any disease  today without paying attention to the profound magnesium deficiencies that  exist in nearly 100 percent of sufferers of chronic disease. We could easily  say the same for bicarbonate and iodine and when we pay attention to all three  at the same time our work in helping people recover from their suffering and  pain is greatly eased. This is especially true when it comes to neurological  diseases.</p>
<p><span class="paragrafo"> </span>The central nervous system is  extremely sensitive and reacts to a combination of factors that allopathic  doctors don’t normally touch down on. Toxic exposures, nutritional deficiencies  and emotional anguish converge most pointedly on the nervous system with often  catastrophic results. As we will see below one of the main disasters facing  people today are wide ranging exposure to both mercury and aluminum; metals at  the top of the list that cause neurological damage.</p>
<p><span class="paragrafo"> </span>Toxic  substances, such as mercury, which the body is chronically exposed to,  accumulates in the brain, pituitary gland, CNS, liver, kidneys, etc. and <strong class="vermelhoBordo">can damage, inhibit, and cause imbalances at very low levels of exposure</strong>. Heavy metals can cause major  neurological, immunological, and metabolic damage.</p>
<p><span class="paragrafo"> </span>Each individual will be seen to have  their own unique combination of neurological, endocrine, and enzymatic  imbalances along with autoimmunities that result from the above factors. Symptoms  will vary resulting in different differential diagnoses: multiple sclerosis  (MS), Amyotrophic Lateral Sclerosis (ALS), Alzheimer’s Disease (AD), or  Parkinson’s Disease (PD), Systemic Lupus Erythematosus (SLE), and eve  rheumatoid arthritis (RA) and chronic fatigue syndrome (CFS).</p>
<p><span class="paragrafo"> </span>Multiple Sclerosis is difficult to  address, both because the symptoms are so variable and treatments are often  ineffective. This disease affects the central nervous system by damaging the  myelin sheaths surrounding nerves of the brain and spinal cord. Primarily  affecting teenagers and young adults of Northern European descent, the disorder  begins between ages 10 and 50 in almost all affected individuals. About 400,000  people in the United States  have MS; twice as many women as men.</p>
<p><span class="paragrafo"> </span>Although the cause remains  officially unknown, it is widely thought to begin as an autoimmune <strong class="vermelhoBordo">inflammation with magnesium deficiency at the core</strong>.   In<strong class="vermelhoBordo"> </strong>studies it’s been shown  that there was a significantly  lower value of magnesium than that seen in control cases. The most marked  reduction of magnesium content was observed in CNS white matter including  demyelinated plaques of MS samples.<a id="_ednref1" name="_ednref1" href="#_edn1">[1]</a></p>
<p><span class="paragrafo"> </span><a href="http://www.ancient-minerals.com/">Magnesium</a> protects the cells from  aluminum, mercury, lead, cadmium, beryllium and nickel. Evidence is mounting that  low levels of magnesium contribute to the heavy metal deposition in the brain  that precedes Parkinson´s, multiple sclerosis and Alzheimer´s. Research has  shown that the symptoms of MS are very similar to <a href="http://imva.info/index.php/mercury-medicine/">Mercury poisoning</a>.<a id="_ednref2" name="_ednref2" href="#_edn2">[2]</a> Mercury is a primary cause of  inflammation in our bodies.</p>
<p class="alinharCentralizar"><em>The rate of relapse in multiple  sclerosis was found to be<br />
decreased with dietary magnesium  supplementation.</em><a id="_ednref3" name="_ednref3" href="#_edn3">[3]</a></p>
<p><span class="paragrafo"> </span>Magnesium deficiency causes and  underpins chronic inflammatory build ups. Inflammation is the missing link to  explain the role of magnesium in many pathological conditions. Dr. Mazur says,  “Magnesium deficiency contributes to an exaggerated response to immune stress  and oxidative stress is the consequence of the inflammatory response.”  <a href="http://magnesiumforlife.com/transdermal-magnesium/magnesium-deficiency/">Magnesium deficiencies</a> feed the  fires of inflammation and pain and it is magnesium that modulates cellular events  involved in inflammation<strong class="vermelhoBordo">. </strong> <strong class="vermelhoBordo">Increases in extracellular magnesium  concentration cause a decrease in the inflammatory response</strong> while  reduction in the extracellular magnesium results in cell activation.</p>
<p class="alinharCentralizar"><em><a name="arrive"></a>Magnesium is central to  immunocompetence and<br />
plays a crucial role in natural and adaptive immunity.</em><a id="_ednref4" name="_ednref4" href="#_edn4">[4]</a></p>
<p><span class="paragrafo"> </span>MS sufferers have a wide variety of  symptoms that often begin rather abruptly and proceed at a highly variable and  unpredictable pace. Common early symptoms include numbness, pins and needles  sensations, incoordination, weakness especially in the legs, painful loss of  vision in one eye, double vision, dizziness, pain at various sites, urinary  symptoms and impotence. Symptoms of MS that are also symptoms of magnesium  deficiency include muscle spasms, weakness, twitching, muscle atrophy, an  inability to control the bladder, nystagmus (rapid eye movements), hearing  loss, and osteoporosis.</p>
<p class="alinharCentralizar"><em>What is essential to remember about  treating pain with magnesium is<br />
that it treats both the symptom and the cause of pain. Meaning the<br />
cause of the pain can often be traced  back to a magnesium deficiency.</em></p>
<p><span class="paragrafo"> </span>Researchers have found oral magnesium  therapy effective on patients with multiple sclerosis. In one formally reported  case a 35-year-old woman suffered with severe spastic paraplegia resulting from  multiple sclerosis (MS). A significant improvement in the spasticity was found  after only 1 week from the onset of the treatment on the modified Ashworth  scale, an improvement in the range of motion and in the measures of angles at  resting position in lower limbs.<a id="_ednref5" name="_ednref5" href="#_edn5">[5]</a></p>
<p><span class="paragrafo"> </span>Nystagmus is characterized by an  involuntary movement of the eyes, often noted as a shaky or wiggly movement and  has been directly tied to magnesium deficiencies.  People with MS also have higher rates of  epilepsy than controls.  Epilepsy has  also been linked to magnesium deficiencies. Without doubt magnesium  supplementation accompanied by pH control via diet and the use of sodium  bicarbonate will do wonders for not only Multiple Sclerosis patients but also  Alzheimer’s and Parkinson’s disease sufferers.</p>
<p class="inContentTitle"><strong>Iodine</strong></p>
<p><span class="paragrafo"> </span>The  relatively low prevalence of multiple sclerosis in Japan, despite its temperate  latitude, has puzzled many researchers. We know though that their soils have  some of the world’s highest known levels of iodine caused by the use of seaweed  as a fertilizer. Deficiencies of this essential trace element appear to be  associated with many diseases, or birth defects, including goitre, cretinism,  multiple sclerosis, amyotrophic lateral sclerosis and cancer of the thyroid and  nervous system. Although the evidence is weaker, iodine deficiency may also be  implicated in Alzheimer&#8217;s and Parkinson&#8217;s diseases. It should be obvious to  physicians that mineral deficiencies are at the center of chronic diseases,  which can be largely avoided if appropriate replenishment is stressed.</p>
<p><span class="paragrafo"> </span>People  with MS may also have low levels of selenium or of glutathione peroxidase, an  enzyme produced from selenium. A theory explaining the pathogenesis of MS  concerns an increased stickiness of cellular plasma membranes, hampering normal  vascular function of the brain. In agreement with that theory researchers have  found significantly lowered selenium values and lowered glutathione peroxidase  activities.<a id="_ednref6" name="_ednref6" href="#_edn6">[6]</a></p>
<p class="inContentTitle"><strong>MS and Mercury Exposure</strong></p>
<p><span class="paragrafo"> </span>Dental  amalgam is documented by medical studies and medical lab tests to be the  largest source of both inorganic and methyl mercury in most people who have  several mercury amalgam fillings. Very low levels of exposure have been found  to seriously affect individuals who are immune sensitive to toxic metals, or  have an inability to detoxify metals    due to such as deficient sulfoxidation or metallothionein function or  other inhibited enzymatic processes related to detoxification or excretion of  metals.</p>
<p><span class="paragrafo"> </span>Amalgam  exposures are commonly above government health guidelines. This is due to  continuous vaporization of mercury from amalgam in the mouth, along with  galvanic currents from mixed metals in the mouth that deposit the mercury in  the gums and oral cavity. Mercury is one of the most toxic substances in  existence and is known to bioaccumulate in the body of people and animals that  have chronic exposure.</p>
<p><span class="paragrafo"> </span>A  large epidemiological study of 35,000 Americans by the National Institute of  Health, the nation&#8217;s principal health statistics agency, found that there was a  significant correlation between having a greater than average number of dental  amalgam surfaces and having chronic conditions such as epilepsy, MS, or  migraine headaches. MS clusters in areas with high metals emissions from  facilities such as metal smelters have been documented.</p>
<p><span class="paragrafo"> </span>Mercury  has been found to accumulate preferentially in the brain, major organs, hormone  glands, and primary motor function related areas involved in ALS- such as the  brain stem, cerebellum, rhombencephalon, dorsal root ganglia, and anterior horn  motor neurons, which enervate the skeletal muscles.</p>
<p><span class="paragrafo"> </span>Mercury  and magnesium deficiencies are at the root of inflammation so it is important  to understand that chelation of mercury will relieve many of the problems  caused by it, and that magnesium will protect our cells from the inflammation  that mercury causes. Magnesium is a necessary factor in chelation, for without  it chelation will not be successful.<a id="_ednref7" name="_ednref7" href="#_edn7">[7]</a> Heavy metals like cadmium, lead, &amp; mercury compete with nutritional  magnesium, keeping it from availability to protect our cells. The healthy cell  wall favors intake of nutrients and elimination of waste products and this is  one of the reasons magnesium is so important in detoxification and chelation.</p>
<p class="alinharCentralizar"><em>Magnesium is a crucial factor in the  natural self-<br />
cleansing and detoxification responses of the body</em></p>
<p><span class="paragrafo"> </span>Because magnesium protects cells  from aluminum, mercury, lead, cadmium, beryllium and nickel, it explains why  re-mineralization is so essential for heavy metal detoxification and chelation.  Magnesium protects the cell against oxyradical damage and assists in the  absorption and metabolism of B vitamins, vitamin C and E, which are  anti-oxidants important in cell protection.</p>
<p><span class="paragrafo"> </span>According to Dr. Russell  Blaylock, low magnesium is associated with dramatic increases in free radical  generation as well as glutathione depletion and this is vital since glutathione  is one of the few antioxidant molecules known to neutralize mercury. Chelation  of mercury and supplementation of magnesium must take place together.</p>
<p class="inContentTitle"><strong>Other Factors</strong></p>
<p class="alinharCentralizar"><img src="http://imva.info/wp-content/uploads/2010/03/clip_image004_0019.jpg" alt="Image" width="216" height="153" /></p>
<p><span class="paragrafo"> </span>Eating a deficient diet is not the only way we can strip our body  of the minerals it needs to protect itself from heavy metal exposure. Many  pharmaceuticals including over the counter medicines drive down magnesium  levels creating ripe conditions for neurological devastation. For example in  1992 researchers reported a case of magnesium deficiency associated with  acetaminophen abuse. Metabolic studies showed that the patient&#8217;s fractional  excretion of magnesium was 12% when her serum magnesium level was 1.0 mg/dL.  Renal biopsy demonstrated severe tubulointerstitial disease. The significant  wasting of magnesium at a time when serum magnesium levels were depressed  suggests renal magnesium wasting syndrome. This defect was related to abuse of  acetaminophen.<a id="_ednref8" name="_ednref8" href="#_edn8">[8]</a></p>
<hr size="1" />
<div>
<div id="edn1">
<p><a id="_edn1" name="_edn1" href="#_ednref1">[1]</a> Magnesium  concentration in brains from multiple sclerosis patientsACTA NEUROL. SCAND. (Denmark),  1990, 81/3 (197-200)</div>
<div id="edn2">
<p><a id="_edn2" name="_edn2" href="#_ednref2">[2]</a> <a href="http://www.flcv.com/ms.html">http://www.flcv.com/ms.html</a></div>
<div id="edn3">
<p><a id="_edn3" name="_edn3" href="#_ednref3">[3]</a> Multiple sclerosis: Decreased  relapse rate through dietary supplementation with calcium, magnesium and  vitamin D; MED. HYPOTHESES (UK), 1986, 21/2 (193-200)</div>
<div id="edn4">
<p><a id="_edn4" name="_edn4" href="#_ednref4">[4]</a> Mag Res.  1992:5:281-93</div>
<div id="edn5">
<p><a id="_edn5" name="_edn5" href="#_ednref5">[5]</a> P. Rossier , S.  van Erven and D. T. Wade  Rivermead  Rehabilitation Centre, Abingdon    Road, Oxford England (DOI)  10.1046/j.1468-1331.2000.00142.x</div>
<div id="edn6">
<p><a id="_edn6" name="_edn6" href="#_ednref6">[6]</a> Biol Trace Elem Res. 1988  Jan-Apr;15:179-203. Selenium in chronic neurologic diseases. Multiple sclerosis  and Batten&#8217;s disease. Clausen J, Jensen GE, Nielsen SA. Institute for Life  Sciences and Chemistry, University of    Roskilde, Denmark.</div>
<div id="edn7">
<p><a id="_edn7" name="_edn7" href="#_ednref7">[7]</a> Magnesium ions constitute the physiologically active  magnesium in the body; they are not attached to other substances and are free  to join in biochemical body processes.5 This is one basic reason magnesium  helps to detoxify toxic chemicals and helps eliminate heavy metals from the  body. Another reason would be the part it plays in glutathione production but  undoubtedly, as Dr. Haley indicates, the Mg-ATP provides the crucial energy to  remove each toxicant. A magnesium ion is an atom that is missing two electrons,  which makes it search to attach to something that will replace its missing  electrons so it is actively and directly involved in diminishing heavy metal  toxicity. Magnesium appears to be a competitive inhibitor of lead and cadmium.  An increased level of magnesium has been shown to eliminate lead and cadmium  through the urine and has also been reported to reduce the toxic effects of  aluminum.</div>
<div id="edn8">
<p><a id="_edn8" name="_edn8" href="#_ednref8">[8]</a> Renal magnesium  wasting associated with acetaminophen abuse. Tuso PJ, Nortman D. UCLA School  of Medicine. Conn  Med. 1992 Aug;56 (8):421-3.</div>
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